I am in a different boat entirly. I believe in having lots of platforms so that you can use any kind of pistol out there if you have to but I also believe in keeping to a single self defense round. That way you can stock pile ammo much easier.
For me it was a 357 magnum. I have double action and single action revolvers, Derringers, 1911 (style), pocket guns, single shot encore and even a lever action rifle in that round.
They all eat the same ammo so I can easily stock up on ammo but I am familure with all these kinds of guns encase I ever have to use some one else's gun. I wish I could find a Glock style gun in 357 magnum,
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 26 of my guns are 45/70 govt, 357 mag, 22 or 12 ga... I believe in keeping it simple. Wish my wife did as well...