Lots of good info in the posts above.
Wife and I shot a couple of large hogs on a Missouri hunt last month.
She used a 44 magnum Ruger Carbine- 240 gr SJSP ammo
I had my 308 winchester, Remington Core-loc 180 gr SP ammo
One shot each.
Found this on another forum. But it helps define shot placement.
Wife paid no attention, put one round of 44 mag into the hogs ear...end of pig.