Originally Posted by JohnKSa
The short story of handgun incapacitation is that it can't be reliably achieved "with the speed needed in a defense situation" unless the central nervous system is significantly damaged. And there is no handgun/bullet combination that can guarantee that since that's primarily dependent on where the bullet goes (is aimed).
I'm soundly convinced that the difference between 9mm ball and the 'best' 10mm JHP will not compensate for 2 1/2" of lateral dispersion from the centerline of the body.
I'm inclined to think if a man hasn't gotten his point across in 4912 attempts, 4913 probably isn't going to do it.