Left-handed bolt action, or a single shot? Nah...
My wife shoots right-handed bolt actions rifles left-handed just fine, and can crank in a follow-up shot just about as fast as a righty. As long as it has a symmetrical stock, I don't see the need for a left-handed bolt action rifle. Just makes it harder to buy and sell, and limits your choice.
My first centerfire varmint rifle was a Thompson Contender with a custom rifle stock and 20-inch bull barrel in .223 from Bullberry Barrel Works. Very accurate gun, but I found it to be a pain in the butt cocking it and pulling that hammer back. Wish I'd had bought a bolt-action instead.