I don't own a Model 60 but I do own a 10/22. For squirrel hunting I would choose the M60 as I believe they are on average more accurate. For fast shooting small game action, I like the more compact 10/22. If I could only have one, I'd take the M60 because I prefer the under barrel tubular magazine over the Ruger rotary magazine.
I seldom shoot my 10/22. It's there if I feel like a big plinking session. I have gravitated to either a Weatherby Mark XXII or TC R-55 for semi-auto shooting.