452/453 are great rifles. the difference between the 452/53 is that the 453 has a single set trigger.
i have a 453 varmit and love it.
I looked at just about every bolt action .22 when I bought it and felt that it was by far the best made and most durable out there. The only one I felt that was close was the Ruger 77/22. The rest to me seem cheaply made thin stamped metal etc...
Sadly it seems the 455 is replacing the 452.
I'd get a 452 while you still can they are excellent.
Link to a good article on the 452