I keep a S&W Model 66 on the table beside the bed. Note I said ON THE TABLE, not locked in a silly gun safe. No kids or visitors in there, so..... But it's always there and ready.
I also keep a short barrel 12 ga double barrel behind the curtains right next to the front door, ready to pick it up if necessary.
In my workshop outside, a Winchester 97 pump right by the door.
Sometimes when I'm walking my property I also carry a 1911A1 in a holster, just in case I see another rattlesnake.