The bore diameters are different, as are the cylinder diameters, which is why you need a cylinder for each cal. However, the same barrel works because the barrel is .224 whereas a 22 long rifle is .222. The gun will be safe and will be fairly accurate, but not like a High Standard or S&W K-22 because of the bore being slightly oversize. For plinking, you will be fine.
Winchester 73, the TFL user that won the west