Panfisher, even though the pythons are making appearances in other areas of S. Fl the bulk of the population is still in the 'glades. Since most of that is either National Park land or state-owned preserves there isn't a whole lot of opportunity for shooting one.
I predict that that will change as the population begins to migrate northward. Most of the snake problem started when Hurricane Andrew blew through back in '91. There were a few reptile distributors that abandoned their property during the hurricane and the storm opened up a bunch of cages releasing a whole bunch of invasive species. Couple that with the deliberate releasings of individuals whos snakes had grown too big to handle and we had a breeding population. In 20 years, they have bred enough to become a real problem. 20 years from now, I'm sure they will have begun to spread out.