Great gun. Your wife has good taste. Lots of history there.
As far as shooting it - I have a bunch of antiques, some from that era, that I shoot maybe once a year just to say I did it. I have a Belgian rifle that began life in 1842 and went through many changes, including a boring of the barrel to make it a shotgun. I had the barrel relined and now it's a great shooter. But it didn't have the historical significance that yours does. Personally, I'd shoot your gun once a year with low loads - having it around for a long time in its great original condition would be more important than hitting targets with it.
Whatever you do with it, it's a great gun. The Real Deal.
And the secret of having your wife buy you guns is...?