I like many others here am a mechanical engineer. My opinion is that loctite has many good applications in guns.
I generally use low strength. I use thread locker for threads and sleeve retainer type for dovetails, etc.
This said, be sure to prep your surfaces with some light sanding and cleaning with alcohol.
When you apply it, you still need to keep bolts in there elastic range and have parts which fit together.
Loctite's place in design is when design, mfg and use came close to design specs, but something just missed. Instead of redesigning, add some loctite. It is a good designer band aid.