Separating shot from powder can be bothersome; but, sometimes it has to be done.
I can't help you with mixed powder. One of the basics of reloading is to have only one type of powder out at any one time (and hindsight is 20/20). Think of these incidents as learning experiences.
Like Big Jim, I've been reloading so long that I've forgotten most of my original reloading errors. One of these days, I'll tell you what happens when you police-up small quantities of spilled powder and temporarily put it in an ash tray.