P290- The gun weighs 20 oz and has a heavy trigger pull. So I would say that your accuracy would be diminished. It does have night sights, though!
Nano- The gun weighs 18 oz and has a heavy trigger pull. It doesn't have night sights on it either. Accuracy is going to be greatly diminished due to the lack of night sights and heavy trigger pull.
Shield- The gun weighs 19 oz and has a reasonable trigger pull (6.5 lbs advertised) and there are aftermarket night sights for it. So, you would be most likely to hit what you're aiming at with this.
Rifles: Custom AR-15, Tavor, Arsenal SGL 31-68
Handguns: Colt Python, XD(M) 4.5" .40, Glock 19, M&P 9mm, Walther PPQ 9mm, FN FNS-9, HK P30S 9mm, Walther PPS 9mm, Browning Buck Mark