I shoot cast lead gas-checked bullets in 30-06, 35 Whelen and 416 Remington Magnum. I use Accurate 5744 powder and aim for around 1800-1900 fps. These loads will give good accuracy (1-1.5 MOA) with a little tuning.
They are a little cheaper to shoot than jacketed bullets, but I buy them already cast. If you mold your own, they will be MUCH cheaper to shoot. Powder charges for these loads are also about 40% cheaper than full house jacketed loads, using AA5744 or SR4759, both of which are designed for this application.