What makes a cartridge romantic (to me) is how long it has been in service.
I think any thing built before 1875 automatically is "romantic"
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 25 of my guns are 45/70 govt, 357 mag, 22 or 12 ga... I believe in keeping it simple