I agree about the .17 buffering up meat. I have an old Marlin 22 wmr with a second hand Swift scope from swfa. Inside of 125 yards it's no problem bagging squirrels and rabbits with cheapo ammunition. The .17 is definitely flatter shooting, but better suited for punching paper and varmint control.
I'd trust a 22 wmr to put down a cuyote inside of 75 yards or so but no further.