I am the op in this thread and I see that every one else is posting there guns. My gun I "harvest" deer with is a Marlin 1894C in 357 magnum (the barrel was cut to 16.5 inches for me when I was a kid) Most of these shots are from my back porch at a range of about 20-60 yards.
When I have to go out and actually hunt I bring my Marlin 1895 in 45/70. These shots typically are about 50-125 yards.
I guess I am use to shooting in the brush with a "pumpkin tosser" for a gun I typically load 405 grain bullets doing about 1600FPS. To me a 300 yard shot just sounds crazy. I know people do it but probably with some thing like a 30-06 or a 300 magnum.
I can shoot "longer distance" for my gun but that is from a bench and with laser and lots of prep. but even from a bench I doubt I could make a 400 yard shot with my 45/70. There are people that could (I have seen in in CAS)
any way I dont know why I am saying all this.
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 25 of my guns are 45/70 govt, 357 mag, 22 or 12 ga... I believe in keeping it simple