Out to a distance of approx 175 yards or so, the 300 Savage, .308, and 30-06 share same trajectory. But beyond this distance, the larger case capacity cartridges have a mathematical advantage.
The 150's you've chosen are famous for their one shot stopping power.
I took this wild hog with my Savage .308 at a distance of approx 75 yards or so. No problems.
Good hunting to you!