Now, now, Gunplummer: How many times I gotta told ya, don't shoot 'em in the eating part?
In seriousness, I pick out a specific spot on an animal where I fully intend for the bullet to hit. I don't know that my skill level is all that wondrous, but it could be that my "pickyness" level is greater than most. Ergo, it has been extremely rare that I ever ruined what I'd call eating meat. And so I figure that any ruination was my fault, not that of the cartridge or bullet.