My preferred stance is whatever I am able to do in the instant that I need to do it in.
Indeed. Note with both weaver and iso stance you can pull that pistol close, which is especially effective for in house. Banging around Miami Vice style is probably not the best way to go.
OT but I started one hand shooting the .22 for "in case of" in the last month and I must say, I've started to really get into into it. All of a sudden it feels natural to shoot cowboy one hand style.