I think of it as more of a, where are you, distance, size of game, ect. I had a friend in college who bought a .300 weatherby mag. He talked me into going hunting with him and he got a pretty decent sized deer with that CANNON of a gun. Now arkansas isnt known for their huge deer and this deer was maybe 60 yards to say the most. It was way overkill. There was way overkill on the shoulder, well there was no shoulderS. Flipped the deer in the air. I've killed deer at 100 yards with my .270 wsm and they dropped right where they stood. Its just not ethical to use that big of a gun. If you were hunting elk, mulies, bears or whatever from 200+ maybe so but a mid size deer from 60 or so yards, come on.
You believe that there is one God. Good! Even the demons believe—and shudder. James 2:19
"I do not fear the man that practices ten thousand kicks one time, I fear the man that practices one kick ten thousand times." Bruce Lee