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Given that the Speer bullet used in the Alliant data is .0005" smaller (.4295") than the XTP of the same weight, and the listed COAL is a longer 1.665 inches, I would back down to 18 grains of MP-300 to start, using the 1.600" COAL to the cannelure. I, personally, would treat 21 gr. as max with the XTP bullet because of the differences already mentioned.
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