You are getting approx 800-825 fps from your current load for the XTP bullets and Universal. You could easily replicate it with cast bullets by dropping down a few tenths of a grain or two with your Missouri cast bullets. As always, start at the minimum in the load book and working back up.
I use a good number of 200 and 250 grain lead bullets in my .45 colts and have had good results with Unique, trail boss, bullseye, and w231. My favorite for powder puff loads is bullseye, but I get best accuracy with unique, but it meters poorly in my lee auto disk, so I don't use it much anymore,
I suggest starting mild and working your way up with any of the powders of your choice. If Universal is working well for you with the XTP I suggest sticking with that powder first.
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