Monolithic bullets like the TSX generally give similar, if not greater, penetration and killing power to cup and core bullets at least one full class heavier. 110 gr .270s compared to 130s. 130 gr .308s compared to 165s. 185 gr .338s compared to 225s.
These lighter bullets usually don't have very good BCs, so they are not really long-range bullets, despite the high velocities they can be loaded to. But out to 300-350 yards, they are real killers.
Congrats on finding some great loads!