I shoot ground squirrels a lot (not on my property) . I figure that it is more humane than the alternative. If the ground squirrels where to live until planting season they will be poisoned which is a slow death. a bullet is much faster and much more humane.
All so they are cannibals and when you shoot one it feeds the others.
as far as hunting, I typically hunt Deer, Elk, Pheasants, Quail, Ducks and Geese. I have hunted in the past Moose, Caribou and Buffalo. I eat all of these. I have shot a few Coyotes in my day but mostly because there where messing with the chickens.
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 26 of my guns are 45/70 govt, 357 mag, 22 or 12 ga... I believe in keeping it simple. Wish my wife did as well...