too much rifle
The 22-250 at factory velocities w/ any bullet is to much gun for turkey.
the .223 w/ the slowest slug possible (heavy if your not a loader) is getting closer. but in std twist rates the heavy slugs will be unstable and likely still be pretty destructive.
The old Hornet and Bee were about ideal turkey rifles, as was the 25-20.
The .22 mag seemed a tad light, but was common.
To bad fmj not legal.