On my old, full sized Vaquero, the original stocks on it made recoil seem worse than it should have been when shooting full powered .45 Colt loads.
I tried smaller, "gunfighter" stocks thinking that they'd allow me to get a better grip with my medium paws, but it was just about as bad.
Then I made myself a set of oversized stocks (couldn't seem to be able to buy 'em) that I customized to fit my hand naturally. These made all the difference in the world for me, and it's very comfortable to shoot now, even with Buffalo Bore 325 grain loads at 1325 fps.
Improving your grip strength will help a lot too, but grips that fit my hand made a big difference for me.