If you go to the Beretta Forum and do some snooping, you'll come across plenty of posts about people "torture testing" various Beretta models. Failures didn't show until the round counts were in the many thousands and beyond. A few hundred rounds will not make the PX4 hiccup (again, my experience is limited to the full size model). It will handle everything I throw at it, from the most garbage of imported rounds to sketchy handloads to premium defensive ammo.
This is not an endorsement to skip out on cleaning your weapon, but rather just piece of mind if you go more than one or two range sessions without cleaning. Also note, a little light grease on the rotating barrel and block assembly will make this gun purr like a kitten after a saucer of cream. Don't overdo it, though. A little dab'll do ya.
"It's never my intent to offend, but sometimes I offend with my intent."