I am a 357 magnum fan for self defense so I gravitate toward revolvers though I do own a Coonan Classic that I am thinking of using for home defense. Currently my home defense gun is a 12GA (Remington 870) with 6 rounds of Winchester PDX1 ammo.
My wife uses her Sig P238 for carry and home defense but I am not sure I trust it.
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 25 of my guns are 45/70 govt, 357 mag, 22 or 12 ga... I believe in keeping it simple