I never tried RL22 but have shot a bunch of 3481 in past it worked OK but now am using IMR 4350 with 115 noslers and 120 Hornady HP.
pet load always shoots under 1" MOA
49 gr IMR 4350
CCI 200 primers
either 115 nosler BT or 120 Hornady HP
This is a max load in my Pro Hunter so you must work up to it, primers are flattened out, but cases last about 12 loadings.