I couldn't tell you how many times some of my range pick-ups have been loaded, Steve. I don't run them hard, generally 800-850 fps from a 4" tube and when the primer pockets get loose I discard them, as I would with any other caliber.
On another forum, I recently found a "40 reloading" thread in which a high percentage of the participants viewed the process as roughly akin to capping live volcanoes or super-gluing the hide back on a PO'ed crocodile. They weren't overly tolerant of anyone attempting to 'cloud the issue with logic' either, so I left them to their flash powder and animal sacrifices.
As in most things, moderation is key to success in loading the .40 S&W.