So far, I've been able to try 9mm, 40S&W, 10mm Auto, 45ACP, and 223Rem and they all seem to feed equally well. I personally don't have any purpose to make it feed rifle cases beyond 223/5.56, but it could be easily adapted to feed 308 or 30-06 if one was so inclined.
Not knocking Hornady but it makes you wonder why they are charging almost $400 for their system (feeder plates included).... I guess the answer to that is "because they can". Obviously people are willing to pay for it.