ClemBert & Fingers McGee are spot on. What I found though was the recoil from those loads is substantial to say the least, not to mention 40gr of powder will eat up a pound of powder quickly.
I'm a big proponent of "Gallery Loads" for 45 Colt. For reduced recoil you can use 20gr 3f and then top off the brass with filler. Seat a .454 round ball and lightly crimp at the equator of the ball. You will probably want some lube around the edge of the brass before seating the ball, I was using SPG sticks and they work good.
Since then I've changed over to using EPP Ultra Gamer 150gr RN bullets that are pre-lubed for Black Powder. Less steps to the reloading process and they shoot great.