Yes, it should work just fine.
The only possible kicker MIGHT be differences in rim diameter. The .45 Long Colt has virtually no rim. Standard is .512, while the standard for the Schofield cartridge was .522.
This caused some issues in years past trying to load the Schofield cartridge in to Colt cylinders.
"The gift which I am sending you is called a dog, and is in fact the most precious and valuable possession of mankind" -Theodorus Gaza
Baby Jesus cries when the fat redneck doesn't have military-grade firepower.