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The full profile meplat of a .45 Colt would be devestating and you would get excellent penetration. Look at the performance of the Buffalo Bore 150 grain hard cast .38 special that will do 900 fps in a 1 7/8" J frame and gives two feet of straight line penetration. Penn Bullets is the only manufacturer making a .45 225 grain wadcutter and it's good to know Saco is making a wadcutter mold. I think you will be very happy with the results and what a sef-defense round - an 11.5 mm .45 Colt wadcutter is nasty.
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