I am a heavy grain kinda guy. thats to say I love the heavy grain stuff.
Google and read up on "sectional density".
I prefer to stick with what's considered the "standard" for each
(158 for the .357 and 240 for the .44, etc..)
If I desire to move up in bullet weight, I tend to increase the caliber instead of the actual bullet.
For instance, if I want to shoot a 200 grain, I'll use a 240 in a .44mag and adjust the velocity as required.
To each their own though. If going heavy for caliber is what you prefer, then go for it.