I really don't see anyone lining up to be the test subject to see how much carnage the various loading for the .50 BMG will create or how big a hole it will make...
I think we can all agree that it will kill anything walking on 2 or 4 legs. It may give you a little more lee-way for a poor shot to be a kill shot than some of the smaller arms used by the Military because of the hydrostatic shock created, but I for one don't count on Hydrostatic Shock alone to put something down when I'm out hunting.
"Laws that forbid the carrying of arms...disarm only those who are neither inclined nor determined to commit crimes...Such laws make things worse for the assaulted and better for the assailants; they serve rather to encourage than to prevent homicides, for an unarmed man may be attacked with greater confidence than an armed man." - Thomas Jefferson, 1776