You're way the heck out in the woods or desert or whatever. You see a snake. Under what possible circumstances is shooting it a good idea?
Because they are mighty tasty floured and fried.
I love the 10mm, especially in a 1911 style pistol, but if I was really concerned with "danger" in the wilderness I'd take the 44 mag. Not everyone can shoot a 44 well enough to stake their safety on it, though.