10mm in a Glock 29 is my go-to gun in the wilds of Michigan where black bear is the biggest predator you're liable to encounter, and cougar and lynx are seemingly even rarer. Until I got my G29, it was my old faithful Colt Delta Elite. I'm a firm believer in 10mm ever since the 80s. If I was ever to venture into Grizzly country though, even the .44 mag would be woefully inadequate to me, and I would be far more comfortable with my SAR-48 with several 20 round mags. Personally, I just don't think you can swat those creatures too hard, and I am in awe of the people that live there and contend with that possibility every day.
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I am the weapon; my gun is a tool. It's regrettable that with some people those descriptors are reversed.