If it's based on moon clips, yes. And any 10mm DA revolver you buy SHOULD be - you'll have a damned difficult time ejecting 'em otherwise

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If it's a 10mm SA revolver then no, that cylinder can't take 40S&W. Can't use moon clips, therefore you have to headspace off the forward rim same as an autoloader does, and the 40S&W shells would drop in too far.