Shot 5 doe last weekend with a 308 using Speer 125gr TNTs. Head or neck shots, and they dropped right away. Heart/lung shots, they ended up running/stumbling 50-75yds and dropped. In all instances, was able to use all quarters, and lost maybe a couple pounds of meat from each deer.
These were all 90-110lb Texas Hill Country deer. So about the same as what you would be hunting.
did see a couple that were shot that weekend with bigger calibers. In every case, shot placement and the angle of the deer determined how much meat was lost. The ones quartering away where bullet exited a shoulder ended up with one forequarter gone for the most part.