In order for these calculations to help, you must have a known load of good accuracy to base the calculations. If one is starting from square one with no acquired loads for a certain caliber, he should start by finding the optimum twist for the bullet and compare it to the twist of the rifle he will be using. If the optimum twist of the bullet is slower than the rifle (ie. optimum twist for bullet = 1 in 12, barrel twist = 1 in 10) then one should start by selecting a lower velocity from the recommended loads. Rbb50, please correct me if i am wrong.
