I guess I am one of the lucky few who can shoot equally as well with both hands. Sure, it takes some practice for me to stay as sharp with my off hand as I am with my strong hand, but I spend a full 1/2 of each session shooting lefty to make sure there are no issues.
As a lad I was truly ambidextrous but went through a plate glass window and sliced through all the tendons on the inside of my left wrist. Took months of exercises and therapy before my left hand was really working well again, and I haven't been able to write or do really fine motor skills as well with that hand since. These days I write right handed, am left eye dominant and can kick as well with either foot.