I've heard mixed reviews on the 22-250 to be honest. I'd prefer to stay away from the .223 just because of the noise factor. I'm not to concerned with ammo because I don't go through that much when hunting. Afterall, I only take a few shots. Most of the hunt is walking, glassing and sitting. Just like any other hunt, ha ha!
Let me ask this, if you had one rifle choise for groundhog hunting, what would you choose?