At some point the benefits from a large scope start to become negated by the side effects. The rise above bore axis and weight are the primary disadvantages, but I'll admit those are problems for hunters, not paper punchers typically.
Leupold has made improvements with their new line of large objective scopes (VX-L - I think). I really like the large objective for dusk/dawn hunting, but I think 72mm is a bit excessive. JMO, but I am interested in hearing other perspectives.
la plus belle des ruses du diable est de vous persuader qu'il n'existe pas!