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With all those criteria, I can tell you what I have found to be very comfortable:
240 gr SWC and 4.5 gr of Accurate #2
200 gr RNFP and 5.5 gr of AA #2
I use OTB's Laser-Cast lead bullets, but this should be fine with any lead bullet of the same weights.
AA #2, like almost all AA handgun powders is tops in metering.
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