Either one can be reloaded or even operated one handed if you have been trained properly....and providing the semi auto is a full size 1911.
You can open the cylinder on a Smith one handed by sliding your middle finger into the trigger guard pushing the thumb latch with your thumb and pushing the cylinder to the side with your trigger finger. Set it down, set it between your knees or stick it under your armpit and reload. Some speedloaders using the push button technique and you are good to go.
The standard (and well worn) 1911 can be operated one handed easily. Put a magazine into the mag well, grasp the gun with your thumb on the grip safety back and your fingers on the top of the slide and close your fist. The slide will move forward. Release and the round is chambered. Or you can just stick the guide plug part of the slide against a table top and push it down and load the peice, providing you don't have a full lenght guiderod in it.
Now, the thing is this. In an emergency, either is as good as the other.However one handed manipulation of a revolver is a bit safer. At no time is the hammer cocked over a live round, without the safety on.
Also, remember, when it comes to loading magazines one handed, stuffing rounds into a cylinder with one hand is a lot easier.
Then there is dissasembly and cleaining. Is a lot easier to clean a wheelie with one hand than take apart a semi auto and reassemble it.
So, if you permanantly lost the use of one hand, you would be better off with the wheelgun than the bottom feeder.