Accuracy in most my rifles is right up there with match grade bullets.
I had a bad experience using Nosler BT in my M7 .308 but it doesn't appear to be the fault of the bullet = 4-5 shoots in right place but the deer just wouldn't die. Full+ expansion & penetration - to the other side.
Still can't explain it ... again, not a fault of teh bullet.
Never used 'em for any other big game.
165s at about 2400 fps are hell on marmots.
A buddy of mine uses 180s in his .30-378 (~3600 fps w/180s = yikes!) for elk. Swears by 'em & has yet to not kill one outright.
Seems a bit frangible for the bigger game.