You can order the load book for .45 colt. I think they cost about $10.95 and have every bullet, every powder. For example, I use 185 gr. Sierra bullets, with Unique powder in my Uberti .45 colt. Starting load is 9.0 gr of Unique at 950 fps. Max load is 12 gr. at 1150 fps. There is no cannelure with these bullets, I did not roll crimp them and they work great. There are loads for cowboy shooting and loads for hunting.