Glad to help.
WESHOOT2 pretty much hit it on the head. The 300 gr version should penetrate deeper, and would be my choice for hogs, or anything larger than deer. I am quite sure it will work very nicely on deer as well. I have always preffered the lighter XTP's on deer, but I think I may give the 300 gr loads a try on deer.
The loads you mentioned should be giving you plenty of velocity, esp. out of a 12'' T/C barrel.
From a penetration standpoint, higher impact velocity usually means less penetration. Conventional bullets expand more rapidly at higher velocities, losing weight and therefore inertia quickly. This isn't a bad thing neccessarily, especially on deer sized game.
That said, XTP's are wonderful hunting bullets. They expand very well,while retaining enough weight and shank length to penetrate completely.
Again, I am glad to help, and hopefully you can find that " perfect load".